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It can be concluded that EAM-2201 has the opportunity to induce in vivo pharmacokinetic drug interactions when co-administered with substrates of CYP2C8, CYP3A4 and UGT1A3, and is evaluated in pooled human liver microsomes.Summary: Semiempirical interatomic potentials have been made for Al, α−Ti, and γ−TiAl throughout the embedded atom method